can you stay on glp 1 for life Variable weight-loss and cardiovascular benefits were seen with GLP-1 drugs in a systematic review and network meta-analysis, but effects quality of were less clear. https://www.medpagetoday.com/primarycare/obesity/122142 New analysis of GLP-1 drugs

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Chronic treatment with a melanocortin-4 receptor agonist causes weight loss and improves insulin sensitivity in diet-induced obese monkeys. J Clin Endocrinol Metab