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The study authors themselves wrote: "The protective effects of semaglutide on the human knee joint should be interpreted with caution and require further validation" [28]
It may be related to estrogen, which has anti-oxidative properties and neuroprotective effects
Studies found that HDL in the plasma of CVD patients with high TMAO levels was significantly reduced, resulting in inhibition of the RCT pathway and cholesterol accumulation in macrophages (64)
Semaglutide is showing that treating metabolism can also change liver outcomes
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