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Peak concentration occurs within 1 to 3 days
Harlan, B
The antimetabolite nature of MTX and its inhibitory effect on many important metabolic enzymes prompted us to study the consequences of MTX treatment on cellular metabolism
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These side effects tend to be worst in the early weeks of therapy or after dose increases
Relevant to research involving gastrointestinal biology, tendon, ligament, muscle, and connective tissue environments
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