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Symptoms are often most pronounced during the initial dose titration phase and may improve as the body adjusts to treatment

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10.1053/j.gastro.2007.08.022 59 LeighlN

Tirzepatide is structurally based on native glucose-dependent insulinotropic polypeptide (GIP) and functions as a dual GIP and GLP-1 receptor agonist, whereas exendin-4 forms the basis of exenatide, a selective GLP-1 receptor agonist

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