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As millions take these medications for long periods of time, unexpected GLP-1 side effects are starting to emerge
These can help track any changes potentially brought on by semaglutide and assist in tailoring your treatment plan accordingly
However, like any medication, GLP-1 medications can sometimes cause side effects that may impact individuals' experiences with treatment
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To our knowledge, no studies have examined the effects of SGLT-2Is on total kidney volume (TKV) in patients with diabetes and only one study has examined the effect of GLP-1RAs [29]
However, if you have been at maximum dose for 12 or more weeks without adequate response, or if side effects prevent further dose increases, switching to tirzepatide is a reasonable next step
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