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21): The description of Carel Le Roux s affiliation has been corrected to note that he is an advisor to Lindus Health
Potential Side Effects at 4 mg, 9 mg, and 12 mg TRANSCEND-T2D-1 reported nausea in 16.4%, 19.5%, and 26.5% of participants receiving 4 mg, 9 mg, and 12 mg, respectively, compared with 3.7% with placebo [9]
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DOI: 10.1113/jphysiol.2013.255364
The work suggests that astrocytes and glial peptides like DBI/ODN are active participants in the GLP-1 pathway, shaping appetite suppression and offering potential as new therapeutic targets
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