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(2021) SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells

2019;102:112742.e1123

We have shown that effective pharmacologic inhibition of GPX4 in PTC cells with direct inhibitor RSL3 induces a robust activation of ferroptosis, increased DNA damage, impaired DNA damage repair response due to reduced p-NPM1 levels, decreased cell viability and cell migration, as well as suppressed spheroid formation and viability in vitro

Hepsin, a cell membrane-associated protease

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The fluorescence of TPE-DCV, however, is selectively turned on by GSH but not Cys or Hcy in the detection medium