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The growth of GLP-1 treatment within diabetes Glucagon-like peptide 1 (GLP-1) receptor agonists have taken the healthcare world by storm, becoming one of the most successful drug classes of all time, reaching an astonishing $110 billion in sales in 2024 alone 1
Semaglutide is known for its effectiveness in controlling blood sugar levels and promoting weight loss, while omeprazole is commonly used to treat acid reflux and reduce stomach acid
GLP-1 also reduces appetite, while GIP may have a role in fat deposition and potentially mitigating some of the nausea associated with GLP-1 receptor agonists
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Therefore, if you are pregnant or breastfeeding, it is recommended to discuss it with your doctor before starting any treatment course
NICE guidance suggests that a 510% reduction in initial body weight produces clinically meaningful improvements in cardiovascular risk factors, glycaemic control, and quality of life
![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
