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The dominant adverse events in both are gastrointestinal nausea, diarrhea, vomiting, and constipation and in both they are dose-dependent and tend to ease as the body adapts to gradual dose escalation

Clinical trials have tested weekly doses ranging from 1 mg to 12 mg, with gradual titration used to improve tolerability and minimize gastrointestinal side effects

There have been reports of individualsboth women and menexperiencing yeast infections while on certain types of these drugs

Some patients may experience hunger-related sleep disruption as they adjust to decreased appetite and smaller portions