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The anatomical distribution of GLP-1R throughout the reproductive system and several preclinical evidence support that GLP-1 can modulate the HPG axis activity at different levels, thus connecting reproductive functions, metabolic system, nutrition, and energy homeostasis mechanisms
According to Bonaca and colleagues, improved blood flow translates to enhanced quality of life, demonstrated by the 2025 results of the STRIDE trial, in which semaglutide significantly increased walking distance and improved function in patients with peripheral arterial disease and type 2 diabetes
However, you should always inform the person drawing your blood and the provider reviewing the results about all medications you are taking, as they will interpret your glucose and insulin levels based on that information
10.1053/j.gastro.2019.01.262 Gastroenterology 101 TaguchiK.FujikawaN.KomatsuM.IshiiT.UnnoM.AkaikeT.et al (2012)
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