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while riboflavin (vitamin B2) supports cellular metabolism

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Inflammation is also known to be a key factor in the development of AS: the aggregation of white blood cells, mainly macrophages, is a significant feature of AS from its initial to its late stage (116)

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It may cause damage and apoptosis of TECs through multiple mechanisms, including mitochondrial dysfunction, oxidative stress, regulation of HIF-1, and alteration of extracellular matrix ( 3.4 Inflammation Inflammation plays a crucial role in the pathophysiology of DKD

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