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Part I: intracranial surgical procedure
Single-cell RNA sequencing, spatial transcriptomics, metabolomics, and imaging mass cytometry can distinguish whether therapy alters neuronal stress, astrocyte lactate programs, microglial glycolysis, endothelial angiogenesis, or pericyte detachment
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GLP analogs do not damage the kidneys, but there have been cases of acute renal failure due to dehydration secondary to vomiting/diarrhea
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