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10.1128/JVI.00603-16 15 CantonM.Snchez-RodrguezR.SperaI.VenegasF

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Future investigations should implement standardized exercise prescriptions, longer follow-up, and preregistered multicenter designs to ensure methodological consistency and improve translational relevance

Current Phase 3 trials (expected to report results in 2027) are exploring doses ranging from 4mg to 12mg weekly, with some protocols testing up to 16mg

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