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Recent observational studies have indicated that DPP4 inhibitors may exert a positive influence on baseline nigrostriatal dopamine degeneration and may improve long-term motor outcomes in PD patients with concurrent diabetes [97-101]
As a result, clinicians must rely on clinical judgment and individual patient response
Some are fixable
The medications appear to reduce neuroinflammation and may influence brain dopamine levels, contributing to these neuroprotective effects ^8
16, Sonthalia, Sidharth, et al
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