Embedding O 3 nanoparticles in MHPCH produced a thermoresponsive composite hydrogel (O 3 NPs@MHPCH) that lowered VEGF and inflammatory cytokines, alleviated synovitis, reduced cartilage injury, and inhibited subchondral trabecular remodeling (Wu H
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The hemolysis ratio was calculated by the following formula: Hemolysis ratio (%) = (OD sample OD negative ) / (OD positive OD negative ) 100
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However, some may experience mild, temporary irritation, redness, or even minor breakoutsoften referred to as 'copper peptide uglies'especially when first starting or using higher concentrations