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food intake and, where justified, pair-fed controls

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FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes

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Participants who were given a higher dose of AOD-9604 (10 mg/day) did not lose more weight