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Patients with a history of certain conditions , including pancreatitis, severe kidney disease, gastroparesis, or type 1 diabetes, should discuss risks carefully with their provider before starting treatment

They transitioned Maria to a different GLP-1 receptor agonist with a lower incidence of gastrointestinal side effects

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Studies have looked into its effects on glucose metabolism, insulin sensitivity and lipid metabolism with research suggesting benefits for metabolic dysfunction and fat accumulation patterns

These data suggest the possibility that GIP signaling, as well as GLP-1 signaling, has a protective effect on blood vessels