Practical Considerations Side Effects While highly effective, GLP-1 medications can cause gastrointestinal side effects such as nausea, constipation, or diarrhea
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In Conclusion Until there is more evidence-based research on the impact of GLC-1 receptor agonists on anesthesia, specifically conscious sedation, DOCS Education recommends a medical consult with the patients PCP or endocrinologist, and absent the strong recommendation to the contrary from their prescribing physician, have the patient withhold their weekly injectable GLP-1 receptor antagonist one week before sedation, and their daily GLP-1 receptor agonist on the day of the sedation appointment, and be NPO 6 hours before the appointment as usual
Currently, there are limited clinical trials evaluating the efficacy of these two drugs in MASLD