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The effectiveness depends on what is being combined and which problem each treatment is intended to address
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The collagen fibers that give tendons their strength become less organized and more prone to fraying
Inhibition of dipeptidyl peptidase-IV activity by metformin enhances the antidiabetic effects of glucagon-like peptide-1
Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met + SU): a randomised controlled trial
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Diabetology & Metabolic Syndrome, 6 , Article 80
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