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Thats because these medications work by reducing appetite and helping you feel full longer, so when you stop taking them, your hunger may return, and this can make it harder to stick to a lower-calorie routine
Laboratory research record on GLP-1S [PMID: 40798974] PubMed laboratory record discussing GLP-1S in a research context
Leptin has been shown to inhibit the production of this hormone as an anorexigenic mechanism [27]
That said, mood changes can have multiple causes, and stopping GLP-1 therapy comes with its own considerations
G.HabeggerK.SpenceJ
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