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doi: 10.1056/nejm200003233421202 230 RidkerP

Unlike single-receptor GLP-1 agonists or dual GIP/GLP-1 agonists, Retatrutide combines three distinct mechanisms into a single peptide

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Reduced hunger stimulation : Ipamorelin is designed to trigger growth hormone release with minimal appetite increase, making it more suitable for weight-loss regimens

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Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI