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300 Furthermore, loss of MLL3/MLL4 in the TME silences enhancers and components of the RISC complex, inducing endogenous dsRNA stress and GSDMD-mediated pyroptosis, which can be harnessed to boost CD8 T-cellmediated responses

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This protective shell acts as a biological "Trojan Horse," shielding the fragile antioxidant from digestive enzymes and stomach acid as it travels through the gastrointestinal tract