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However, this has opened the door for their potential use in a variety of diseases in which obesity is an exacerbating factor

Whilst emerging evidence suggests the extensive therapeutic potential of GLP-1, further studies are needed to fully elucidate its mechanisms and its clinical applications in gastrointestinal disorders

These studies suggest that strategies combining NAD + boosting with inhibitors of NAD + -consuming enzymes could be a promising approach to mitigate axon degeneration

thus, the phenotype is manifest fully in males whereas female heterozygotes display varying degrees of G6PD deficiency, due to alternate X-chromosome inactivation 3,4

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