The review further highlights emergent research on "next-generation" therapies with weight-loss efficacy of up to about 24% in clinical trials, approaching weight-loss magnitudes reported in some surgical interventions
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de Oliveira B, Oliveira BC, Deutsch G, Pessanha FS, Thire R, de Castilho SR
discuss an appropriate target with your clinician or dietitian, especially if you have kidney disease
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Weight loss results primarily from reduced energy intake supported by physiological changes in hunger and satiety