Off-label compounded sermorelin remains widely used in adult anti-aging and hormone-optimization practices
The mechanisms are fundamentally different: steroids suppress inflammation temporarily, while peptides aim to modulate inflammation while promoting regeneration
[3] Goldstein, A.L., et al
Wu J, Zhou L, Liu J, et al
Beginner Tips Before Trying Peptide Research Set realistic expectations: subtle metabolic optimization, not dramatic transformation
For randomised clinical trials, the Jadad scale ( To complement the Jadad score, the Cochrane Risk of Bias Tool (RoB 2) (Sterne et al., 2019) was also used for RCTs to provide a domain-based qualitative evaluation, assessing risks related to selection, performance, detection, attrition, and reporting