Studies administering EGCG to Beagles indicated that fasting increased the likelihood of hepatotoxicity compared to animals that were fed prior to treatment (234)
Biochem Biophys Res Commun , 2001;280(1):1328
Across human studies and reviews, adverse effects are uncommon at typical supplemental intakes, and when side effects do occur, they are usually mild and gastrointestinal in nature.12 13 44 A safety-focused review published in European Review for Medical and Pharmacological Sciences summarized available clinical and non-clinical data on myo-inositol and reported that only very high intake (around 12g per day) was consistently associated with side effects specifically mild gastrointestinal symptoms such as nausea, gas/flatulence, and diarrhea.44 The authors also noted that the severity of these effects did not increase with higher doses
doi: 10.1074/jbc.M608175200 106 WiestDLBurkhardtJKHesterSHortschMMeyerDIArgonY
Thiamine (B1) 100mg/mL: Improves your immune system, and helps convert fat and carbs into energy
L-Carnitine is involved in energy metabolism, it transports the long-chain fatty acids into mitochondria to be oxidized for energy production