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Importantly, tirzepatide carries an FDA boxed warning for risk of thyroid C-cell tumors, and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
Medical therapies are an important treatment option, particularly for patients who may not be suitable for surgery or those with persistently high levels of GH/IGF1 following surgery
Others pursue it for general vitality and as one component of a longevity plan
Important: maintain pH above 5.0, as the copper ion dissociates in acidic conditions
doi: 10.1080/07315724.2005.10719490 77 MissoNLABrooks-WildhaberJRaySVallyHThompsonPJ
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