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Unlike dietary L-carnitine obtained from red meat, which the body absorbs highly efficiently, oral L-carnitine supplements have a relatively low absolute bioavailability, typically ranging from 14% to 18%

2011 Jan;91(1):151-75

On the contrary, microsomal GSTs, also known as MAPEG (membrane-associated proteins involved in eicosanoid and glutathione metabolism), are integral membrane proteins which are not evolutionary related to the other major classes

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And people may need vitamin B 12 injections to lessen this risk of deficiency, leading to pernicious anemia

Provides systemic distribution with relatively consistent absorption