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How the FDA labels the signal - whether as a boxed warning, a dose-titration requirement, or a monitoring recommendation - will shape the commercial dose-use pattern and therefore the real-world average weight loss at population scale

placebo Approval for the Wegovy oral tablet taken once daily was based on a 64-week long clinical trial with 307 adults with obesity, or overweight with one or more weight-related medical conditions

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No washout period is needed between medications