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Mechanism of Action Copper chelation enabling cuproenzyme activity

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Finally, our experiments with (h)GSH depletion and exogenous GSH treatment allowed us to conclude that (i) both the GSH concentration and the GSH:hGSH ratio play an important role in defense responses and senescence in symbiotic nodules at least partly through the regulation of Cyp15a, TPP , PR1 , and PR10 gene expression