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Exosomes from retinal astrocytes contain antiangiogenic components that inhibit laser-induced choroidal neovascularization
-Average weight loss of 22.5% at the 15mg dose at 72 weeks
Single doses of 42, 140, 420 and 1260 mg intravenously were well tolerated and showed dose-proportional, linear pharmacokinetics, with the half-life increasing with the dose Ruff et al., 2010
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