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doi: 10.1093/ajcn/84.1.289 7
To further confirm these findings, the expression of the hypertrophy-associated biomarkers ANP, BNP, and -MHC was assessed at the mRNA level in primary cardiomyocytes, revealing that all three of these genes were upregulated after 48 h in PE-treated cells, whereas PQQ pretreatment reversed this PE-induced upregulation of these genes (Figure 3G)