No significant concerns in trials
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Glutathione s-transferases in pediatric oncology research models [PMID: 22655244] Laboratory literature summary: Glutathione s-transferases in pediatric oncology research models
Figures 2, 4) availability is maintained by de novo synthesis from precursor amino acids, (glutamate, cysteine, and glycine), reduction of GSSG by glutathione reductase (GR), and uptake from exogenous GSH sources across plasma membranes (Figure 4) ( via specific plasma membrane transporters ( FIGURE 3 FIGURE 4 Glutathione cellular distribution Glutathione is found in almost all cellular compartments, including the nucleus (Figures 2, 4)
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Its a paper that has become a North Star for Sikirics work, and he invoked it now to defend his project: The passage does not mention receptors, Sikiric pointed out, suggesting to him that Robert didnt view them as essential for cytoprotection