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One key group includes individuals with pernicious anemia, an autoimmune condition that affects the bodys ability to absorb vitamin B12 from food

doi: 10.1016/j.molmet.2020.100991 51 DourosJDMokrosinskiJFinanB

Immediate medical attention is required if patients experience concerning symptoms alongside the plateau, including: Unexplained fatigue, cold intolerance, or other symptoms suggestive of thyroid dysfunction Unintentional weight gain (rather than plateau) despite continued medication and lifestyle adherence New or worsening symptoms of depression or anxiety affecting motivation and self-care Severe abdominal pain (especially if radiating to the back) or persistent vomiting stop tirzepatide immediately and seek urgent medical attention to rule out pancreatitis Right upper quadrant or epigastric pain, fever, or jaundice, which may indicate gallbladder problems Symptoms of hypoglycaemia (sweating, dizziness, confusion, irritability) in patients also taking insulin or sulfonylureas Development of disordered eating patterns or unhealthy weight control behaviours Patients should also seek guidance if they are considering discontinuing Mounjaro due to plateau frustration

I first wrote about Consumer Lab when it launched around 1999, and I was a health writer at the Washington Post

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