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Berberine may help reduce body weight modestly (about two to four pounds over several weeks) and lower HbA1c levels, but it lacks the robust, consistent results seen with GLP-1 medications like Ozempic, which can produce 15 to 20 percent body weight reductions in clinical trials. Can GLP-1 Supplements Help With Weight Loss

3,6,11,12,30 Patient Counseling Points Sitagliptin, saxagliptin, alogliptin, and linagliptin should be taken once daily and may be given without regard to meals

However, because it activates the GLP-1 pathway along with GIP and glucagon receptors researchers believe similar brain-related effects could occur