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Beyond Mazdutide and Retatrutide, several additional multi-receptor agonists progress through clinical development

For a deeper dive into related GLP-1 side effects, read our guide to why GLP-1 medications cause GI issues

Risks of Rapid Weight Loss Gallstones Muscle loss Electrolyte imbalance Loose skin Mental burnout GLPs do reduce appetite, but too-fast results can backfire, especially if youre not supporting your body with proper nutrition

Liver health: The liver is the primary organ responsible for producing and regulating glutathione levels

Retatrutide is a triple hormone receptor agonist (GLP-1, GIP, glucagon) under Phase 3 investigation

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