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Timing and food intake: Taking B12 supplements with or immediately after meals often reduces stomach upset significantly
Nutr Rev
Starting at the lower end and assessing response before increasing makes sense for most users
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Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs
2) Fortified Drinks and Foods Some fortified foods and beverages are formulated to provide high amounts of B12
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