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Singh S, Chang HY, Richards TM, et al

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The tissue around the navel is denser than the surrounding subcutaneous fat, which can make the injection more uncomfortable and affect how evenly medication absorbs

It is also very crucial for heart and brain function, movement of the muscle, and a variety of other body processes

Whether the metabolic benefits of triple agonism outweigh the heart rate concern is an active area of investigation in the TRIUMPH trials

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