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In 2020, a related study (28) demonstrated that overexpression of miR-140-3p inhibited the proliferation of human cervical cancer cells by targeting down-regulation of RRM2 inducing cell cycle arrest and early apoptosis, while decreasing BCL-2 protein levels and inducing a significant increase in BAX and caspase-3 protein levels
The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age
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doi: 10.3390/biology11121717 85 SilvaLBdos Santos NetoAPMaiaSMdos Santos GuimaresCQuiduteILCarvalhoAet al
These findings demonstrate that GGT activity is sufficient to support GSH catabolism and survival of surrounding cells in cystine-depleted conditions
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