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Notably, the STEP trials demonstrated significant weight reductions in obese participants, forming a robust foundation for semaglutide's approval for weight management (Garvey et al., 2022)

The answer, he says, is yes. The new results represent an undeniable setback, says Paul Edison, a neuroscientist at Imperial College London who was not part of the work

GLP1RA medications mimic the GLP-1 hormone, which regulates insulin, blood glucose levels, and appetite, promoting feelings of fullness

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