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Melatonin role in experimental arthritis [PMID: 15032620] Laboratory literature summary: Melatonin role in experimental arthritis
During this time, participants lost significant fat combined with a low-calorie diet and increased physical activity
To make a diagnosis the symptoms must be present for at least three months, and are associated with soft tissue tenderness which is unrelated to the applied pressure (called allodynia) and often with problems with mood such as depression