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Safety and efficacy of teduglutide (Gattex) in patients with Crohns disease and need for parenteral support due to short bowel syndrome-associated intestinal failure
Injection site reactionsincluding erythema, pruritus, or indurationoccur in approximately 2-5% of patients and typically resolve spontaneously
The mechanism by which GLP-1 RAs potentially increase suicide or suicide attempts is unclear but may involve an overactivation of the hypothalamic-pituitary-adrenal (HPA) axis [7], rapid weight loss [8], and reduced expression of brain-derived neurotrophic factor which may link weight changes to heightened anxiety and suicidal risk [9]
Glutathione can reduce oxidative damage caused by drug and alcohol abuse
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