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The biggest difference in the semaglutide vs tirzepatide discussion is that Semaglutide works only on GLP-1 receptors, while Tirzepatide activates both GLP-1 and GIP receptors

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Post administration of oral carnitine supplements, in addition to a high carnitine diet, 58-65% of the administered radioactive dose was recovered from urine and feces in 5-11 days