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For example, following the induction of intestinal ischemia in humans, a rapid increase in GLP-1 secretion was observed, suggesting a link between endogenous LPS translocation and GLP-1 activation under conditions of barrier dysfunction (Nguyen et al., 2014)
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Degradation From a chemistry standpoint: Lower temperatures can increase aggregation risk over long timeframes at higher concentrations Higher temperatures accelerate chemical degradation pathways Heat speeds chemistry
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