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doi: 10.1001/jama.240.14.1508 105 YoonGKimY-KSongJ
Choong, C
This effect is more common when glutathione is taken in very high doses for an extended period
Moreover, studies based on gene expression data and tissue-specific genome-scale metabolic models have demonstrated that the gut microbiota can influence host amino acid metabolism and contribute to changes in glutathione metabolism [77]
Although DSM-5 diagnosis is defined through multiple behavioral criteria encompassing impaired control, social dysfunction, continued use despite harm, and tolerance or withdrawal, converging clinical and preclinical evidence indicates that the core pathological feature of SUDs is the progressive loss of control over intake (O'Brien, 2005)
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