Pernicious anemia, one of the causes of vitamin B12 deficiency, is an autoimmune condition that prevents your body from absorbing vitamin B12
doi: 10.1155/2017/3494289
This longitudinal observational study monitored Akkermansia levels in the gut microbiome of obese patients before and after an intervention of bariatric surgery
Recent multicenter RCTs have demonstrated that SGLT-2Is, 278,337,338,339 GLP-1RAs, 340 and ns-MRAs 329,341,342 offer significant kidney and cardiovascular benefits, regardless of baseline albuminuria, eGFR, or diabetes status
90 However, ME1 and ME2 seem to be the main isoforms because ME3 is hardly negligibly detected in many assessed mammalian cells
Your body has to convert it before it can be used, and many of the patients who walk in saying Ive taken B12 for years and never felt anything turn out to have been on cyanocobalamin the whole time