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However, when the hydrophobic thickness of the host lipid membrane becomes smaller than the hydrophobic thickness of cholesterol, cholesterol starts to exhibit tilted orientations and can even sequester between the two membrane leaflets in very thin lipid membranes [66, 7274]

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Taylor C, Schonberger N, Lanikova A, Patzschke M, Drobot B, Zidek L, Lederer F (2021) Investigation of the structure and dynamics of gallium binding to high-affinity peptides elucidated by multi-scale simulation, quantum chemistry, NMR and ITC

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Current investigations continue to assess how peptide-based compounds interact within multi-pathway signaling environments, including potential influences on coordinated cellular processes and system-level biological responses in controlled laboratory models