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Adequate intracellular levels of glutathione are required for the proper proliferation and activity of lymphocytes (T-cells and B-cells) and natural killer (NK) cells
Getting it via IV is also effective in bypassing the gut but is cost prohibitive for most
For 15 min drug treatment, trophozoites (3034 h post invasion) were incubated with 50 M MB, 1 mM diamide or 50 mM H 2 O 2
The absorption of non-heme iron, from the lumen of the small intestine, requires that the dietary iron, which is predominantly in the oxidized state (Fe 3+ ), be reduced to the ferrous (Fe 2+ ) state
Imbalance in these regulatory antioxidant mechanisms and lipid peroxidation can eventually lead to ferroptosis 82
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