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Most patients notice early appetite changes within the first 1 to 2 weeks, but measurable weight loss typically starts to appear after 4 to 8 weeks as calorie intake naturally decreases and the body adjusts to the medication

[14] [15] Weight loss can help restore more normal testosterone levels

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Of these, 35 women were treated with Wegovy (semaglutide), one with another GLP-1 drug, Saxenda (liraglutide), and eight with a placebo

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