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In Phase 2 clinical trials at the 12mg dose, women averaged 25.3% body weight loss over 48 weeks while men averaged 22.8% over the same period

DM2: type 2 diabetes, ALA: alpha-lipoic acid, Nrf2: Nuclear Factor Erythroid 2-Related Factor 2, CKD: chronic kidney disease, HbAc1: Glycosylated Haemoglobin, HOMA-IR: homeostasis model assessment of insulin resistance

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Pharmacies may see reduced revenues, margins per fill but higher prescription volumes and more cash-paying patients, potentially balancing the impact

HPLC-MS/MS provides the highest specificity for simultaneous GSH and GSSG resolution